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The University of Southampton
Health AfTer subaraChnoid Haemorrhage (HATCH) Consortium

Output

Peer-reviewed original research articles and reviews:

Pilot GWAS

A Genome-Wide Association Study of Outcome After Aneurysmal Subarachnoid Haemorrhage: Discovery Analysis. Gaastra B, Alexander S, Bakker MK, Bhagat H, Bijlenga P, Blackburn SL, Collins MK, Doré S, Griessenauer CJ, Hendrix P, Hong EP, Hostettler IC, Houlden H, IIhara K, Jeon JP, Kim BJ, Li J, Morel S, Nyquist P, Ren D, Ruigrok YM, Werring D, Tapper W, Galea I, Bulters D. Transl Stroke Res. 2023 Oct;14(5):681-687

Evidence-based interconversion of the Glasgow Outcome and modified Rankin scales

Evidence-based interconversion of the Glasgow Outcome and modified Rankin scales: pitfalls and best practices. Gaastra B, Ren D, Alexander S, Awad IA, Blackburn S, Doré S, Hanley D, Nyquist P, Bulters D, Galea I. J Stroke Cerebrovasc Dis. 2022 Dec;31(12):106845

Haptoglobin treatment consensus

 Haptoglobin Treatment for Aneurysmal Subarachnoid Hemorrhage: Review and Expert Consensus on Clinical Translation. Galea I, Bandyopadhyay S, Bulters D, Humar R, Hugelshofer M, Schaer DJ for the SAH Delphi Group. Stroke. 2023 Jul;54(7):1930-1942

Pilot GWAS protocol

 Genome-Wide Association Study of Clinical Outcome After Aneurysmal Subarachnoid Haemorrhage: Protocol. Gaastra B, Alexander S, Bakker MK, Bhagat H, Bijlenga P, Blackburn S, Collins MK, Doré S, Griessenauer C, Hendrix P, Hong EP, Hostettler IC, Houlden H, Iihara K, Jeon JP, Kim BJ, Kumar M, Morel S, Nyquist P, Ren D, Ruigrok YM, Werring D, Galea I, Bulters D, Tapper W. Transl Stroke Res. 2022 Jan 6. doi: 10.1007/s12975-021-00978-2.

Haptoglobin genotype and outcome after SAH

 Haptoglobin genotype and aneurysmal subarachnoid haemorrhage: individual patient data analysis. Gaastra B, Ren D, Alexander S, Bennett ER, Bielawski DM, Blackburn SL, Borsody MK, Doré S, Galea J, Garland P, He T, Iihara K, Kawamura Y, Leclerc JL, Meschia JF, Pizzi MA, Tamargo RJ,  Yang W, Nyquist PA, Bulters DO, Galea I. Neurology. 2019 Apr 30;92(18):e2150-e2164. doi: 10.1212/WNL.0000000000007397.

Nature Reviews Neurology

Haemoglobin scavenging in intracranial bleeding: biology and clinical implications. Bulters D, Gaastra B, Zolnourian A, Alexander S, Ren D, Blackburn SL, Borsody M, Doré S, Galea J, Iihara K, Nyquist P, Galea I. Nat Rev Neurol. 2018 Jul;14(7):416-432

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